https://nova.newcastle.edu.au/vital/access/ /manager/Index en-au 5 Contribution of Common Genetic Variants to Risk of Early-Onset Ischemic Stroke https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:52000 Tue 26 Sep 2023 11:29:09 AEST ]]> PATJ low frequency variants are associated with worse ischemic stroke functional outcome: a genome-wide meta-analysis https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:47651 PATJ (Pals1-associated tight junction) gene were associated with worse functional outcome at 3-month after stroke. The top variant was rs76221407 (G allele, β=0.40, P=1.70x10−9). Conclusions: Our results identify a set of common variants in PATJ gene associated with 3-month functional outcome at genome-wide significance level. Future studies should examine the role of PATJ in stroke recovery and consider stringent phenotyping to enrich the information captured to unveil additional stroke outcome loci.]]> Tue 24 Jan 2023 14:58:40 AEDT ]]>